Global Plant-Based Clinical Outcomes Registry
GPCOR is building the outcomes registry that turns real patient experience with plant medicine into evidence regulators, payers, and clinicians can actually use.
We take no position on whether these therapies work. We build the system that finds out.
The same validated measures used in clinical trials, administered unchanged so results compare.
De-identification happens inside our own infrastructure. Nothing identifying leaves it.
The evidence gap
Plant medicine has moved faster than the systems built to study it. What exists is fragmented, non-comparable, and rarely followed over time — which means it cannot inform coverage decisions, clinical guidelines, or policy.
Studies use different instruments, different timepoints, and different definitions of the same outcome. Results can't be pooled, so nothing accumulates.
Most data is a single snapshot. Without longitudinal measurement there's no way to see whether an effect holds, fades, or reverses.
Existing evidence over-represents narrow populations. The communities carrying the most chronic disease burden are the least represented in the research about it.
Positioning
This distinction is the reason institutional partners can work with us. We hold it strictly.
How the registry works
Everything before it involves a person. Everything after it involves a record. Once data crosses, no path back to the participant exists — not for us, not for a research partner, not for anyone who compels us.
Eligibility confirmed against protocol criteria. Anyone who doesn't qualify goes no further and no record is created.
Informed consent and HIPAA authorization explained and signed, with a copy and written opt-out instructions given to the participant.
Trained staff enter five identifying fields into a secure intake environment, walled off from the research database.
Our own de-identification engine converts those five fields into an irreversible token. The source values are then purged.
The anonymous record enters the database — exposure, condition, product, and standardized outcome scores, bound only to a token.
Later assessments re-tokenize to the same value and attach to the right record, without anyone storing a name to match against.
Qualified research institutions receive de-identified datasets under written agreement. No token material, no key material, no route back.
Why the line is one-way. Tokenization is a hash, not an encryption — there is no key that reverses it. That's a deliberate constraint, not a limitation. It also means that once a record is de-identified, withdrawing from the registry stops all future collection but cannot retract data already released. Participants are told this plainly during consent, not in fine print.
Governance
Each of these limits what GPCOR is permitted to do. That's the point.
The registry protocol, the consent documents, and every participant-facing instrument go to an Institutional Review Board. Nothing is administered outside an approved version.
Identifying data lives in a separate environment from research data, with separately provisioned access. No single role holds both.
We administer validated measures under the rights we hold, unchanged. An instrument we don't have rights to isn't in the battery.
Every release names the recipient, the approved purpose, and the exact dataset version. Re-identification attempts are prohibited by contract and by the architecture.
Adverse events are escalated to a named clinician on a defined clock, independent of when they surface in a questionnaire.
Access and release are logged immutably. Any change to the instrument or the workflow is versioned and reviewed before it takes effect.
Get involved
If you're managing a condition with plant medicine, your experience is the data that doesn't exist yet. Participation means a baseline questionnaire and short follow-ups over about a year.
Register your interest →Sites administer consent and intake, and receive training and materials. If you already see patients using these therapies, you're already generating the observations we're built to capture.
Talk to us about becoming a site →Academic centers, health systems, and research organizations can access de-identified, longitudinally aligned datasets under written agreement — structured for the analyses you actually need to run.
Discuss a partnership →Contact
Tell us who you are and what you're trying to do. We'll route it to the right person.
For media, research partnerships, site inquiries, and general questions. If you're a prospective participant, use the form to register your interest and we'll be in touch when enrollment opens.
Please don't include personal health information in this message. If you're registering interest, we'll collect what we need through a secure process later.
One short form, about two minutes. It opens in a new tab, so you won't lose your place on this page.
Open the contact formOr email [email protected]